Editor's Note: Standard, internationally preferred terms and definitions are highlighted in blue. Terms and definitions in black are acceptable, but only if the standard internationally preferred terms and definitions are unacceptable for a certain context. Terms highlighted in red are not acceptable in the international standards community. They appear for educational purposes only. Notes and examples included with definitions are illustrative, and are not to be considered part of the standard definition.

Terms often include related terms and/or alternate terms. Related terms may have similar meanings or apply in similar contexts as the main term, and are included to help users choose the best term for their needs. Alternate terms are synonymous with the main term. In the Definitions sections of CLSI documents, related terms are indicated with a single slash (/) between the two terms, and alternate terms are indicated with the use of two slashes (//) between the two terms.

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reproducibility

(measurement) measurement precision under reproducibility conditions of measurement (JCGM 200:2012)

NOTE 1: Relevant statistical terms are given in ISO 5725-1:1994 and ISO 5725-2:1994 (JCGM 200:2012); NOTE 2: For the purpose of immunohematological testing, reproducibility is typically confined to challenging the automated system’s ability to render the same interpretation consistently; NOTE 3: More broadly defined as the agreement between repeated measurements on the same specimen under different conditions; NOTE 4: The closeness of agreement between the results of the measurements of the same measurand carried out under changed conditions of measurement; NOTE 5: Changed conditions may include principle or method of measurement, observer, measuring instrument, location, conditions of use, and time; NOTE 6: Reproducibility conditions include different locations, operators, measuring systems, and replicate measurements on the same or similar objects (modified from JCGM 200:2012); NOTE 7: In chemistry, the terms “between-laboratories,” “interlaboratory,” or “among-laboratories precision condition of measurement” are sometimes used to designate this concept; NOTE 8: The ability of a product, within lots and across multiple lots, to produce the same results, when used in different settings (eg, different sites, different operators, different instruments); NOTE 9: The measure of the closeness of the results obtained when analyzing the same sample more than once; NOTE 10: The measure of agreement between replicate measurements of the same material; NOTE 11: Changed conditions may include principle or method of measurement, observer, measuring instrument, reference standard, location, conditions of use, and time; NOTE 12: Several types of reproducibility are often used in laboratory medicine: “between-assay,” “between-run,” “interassay,” “inter-run,” “interoperator,” “interanalyst,” and “interlaboratory” precision. The operative conditions should always be specified; NOTE 13: As with blood cell counts, viable cells have different properties compared with dead cells, which may limit the duration of day-to-day studies; NOTE 14: The operative conditions should always be specified; NOTE 15: For EP12, reproducibility conditions of measurement may, contain interinstrument or interlaboratory data; NOTE 16: Several types of reproducibility often are used in laboratory medicine: “between-assay,” “between-run,” “interassay,” “inter-run”, and “interlaboratory” precision. The operative conditions should always be specified; NOTE 17: Precision can be affected by different parameters (eg, disk lot, media lot) being used, measurements being made by different operators, or measurements being made over a period of time.

Alternate Term: measurement reproducibility

Project: MM13, POCT14, H58, I/LA33, C43, M51, MM06, H59, I/LA28, GP34, H02, I/LA34, M53, EP21, MM19, MM01, MM20, MM07, EP09, C40, MM22, MM09, H60, EP05, C62, C57, MM23, POCT06, EP19, M52, MM21, H48, POCT04, QMS24, MM17, NBS05, MM24, EP39, H62, EP12, M23, EP12-IG

Related Term(s):
reproducibility condition
(of measurement) condition of measurement, out of a set of conditions that includes different locations, operators, measuring systems, and replicate measurements on the same or similar objects (JCGM 200:2012)


reproducibility

ability of a product, within lots and across multiple lots, to produce the same results, while used under different conditions (eg, different sites, different operators, different instruments)

Project: M50


reproducibility

precision under reproducibility conditions (ISO 15198)

Project: ISO 15198


reproducibility

precision under conditions where test results are obtained with the same method on identical test items in different laboratories with different operators using different equipment (ISO 5725-1)

NOTE: ISO 3534-1 [3.20] defines reproducibility as “precision under reproducibility conditions.”

Project: ISO 15197 (April 2001), GP28, C50

Related Term(s):
precision
1) (of measurement) closeness of agreement between independent test results obtained under stipulated conditions (ISO 3534-1); 2) the closeness of agreement between independent test results from the same sample obtained under prescribed (stipulated) conditions (modified from ISO 5725-1); 3) the closeness of agreement between independent test results obtained under prescribed conditions (ISO Guide 30); 4) closeness of agreement between a series of measurements, under specified conditions, of a substance or biological product

intermediate precision conditions
conditions where test results or measurement results are obtained with the same method, on identical test/measurement items in the same test or measurement facility, under some different operating conditions (ISO 3534-2)

reproducibility conditions
conditions where test results are obtained with the same method on identical test items in different laboratories with different operators using different equipment (modified from ISO 17593)

total imprecision
See and use reproducibility


reproducibility

in bacterial strain typing, the closeness of agreement between results obtained when the same method is applied; a) to multiple isolates representing a single strain (as defined by strict epidemiologic criteria); or b) for replicates derived from subculture of a single isolate; the multiple assessments may be made over time in a single laboratory or in different laboratories

NOTE: Reproducibility in bacterial strain typing is influenced by both technical and biologic factors.

Project: MM11


reproducibility condition

(of measurement) condition of measurement, out of a set of conditions that includes different locations, operators, measuring systems, and replicate measurements on the same or similar objects (JCGM 200:2012)

NOTE 1: The different measuring systems may use different measurement procedures (JCGM 200:2012); NOTE 2: A specification should give the conditions changed and unchanged, to the extent practical (JCGM 200:2012); NOTE 3: The changed conditions may refer to different lots, runs, time (day), technicians, etc.; NOTE 4: For the purpose of immunohematological testing, this is typically confined to challenging the automated system’s ability to render the same interpretation consistently; NOTE 5: In chemistry, the terms “between-laboratories,” “interlaboratory,” or “among-laboratories precision condition of measurement” are sometimes used to designate this concept.

Alternate Term: reproducibility condition of measurement

Project: ISO IEC Guide 99, ILA29, GP16, I/LA21, I/LA33, M51, I/LA28, GP34, H02, MM19, C51, EP09, C40, I/LA26, H60, EP05, C57, MM23, POCT06, EP29, EP19, M52, MM21, POCT04, QMS24, NBS04, EP30, NBS05, MM01

Related Term(s):
reproducibility
precision under reproducibility conditions (ISO 15198)

reproducibility
(measurement) measurement precision under reproducibility conditions of measurement (JCGM 200:2012)


total imprecision

See and use reproducibility

Alternate Term: reproducibility

Related Term(s):
precision
1) (of measurement) closeness of agreement between independent test results obtained under stipulated conditions (ISO 3534-1); 2) the closeness of agreement between independent test results from the same sample obtained under prescribed (stipulated) conditions (modified from ISO 5725-1); 3) the closeness of agreement between independent test results obtained under prescribed conditions (ISO Guide 30); 4) closeness of agreement between a series of measurements, under specified conditions, of a substance or biological product

reproducibility
precision under conditions where test results are obtained with the same method on identical test items in different laboratories with different operators using different equipment (ISO 5725-1)

reproducibility conditions
conditions where test results are obtained with the same method on identical test items in different laboratories with different operators using different equipment (modified from ISO 17593)


 

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